Student Projects
Student Projects
Final group projects — Abdalfttah Academy, Summer 2026
Summer 2026
Bioinformatics 101
Group 1
HBB protein
Comparative Sequence Alignment and Phylogenetic Analysis of Hemoglobin Subunit Beta Protein (HBB) Across Diverse Species
Team
- Rowida Salem
- Jana Ossama
- Alaa Fayez
- Mahmoud Eladawy
Group 2
Penicillinase (β-lactamase enzyme)
Phylogenetic Analysis of OXA-1 β-Lactamase Responsible for Antibiotic Resistance Across Different Bacterial Species
Team
- Mariam Elgharbawi
- Habiba Ahmed
- Youssef Mahmoud
- Kenzi Shawki
- Safaa Shehab
Group 3
Myostatin gene
Comprehensive Bioinformatics and Evolutionary Analysis of the Myostatin (MSTN) Gene
Team
- Nour Abdo
- Nadeen Ahmed
- Hasnaa Mahmoud
- Haneen Mamdouh
Group 4
TP53 gene
Comparative Sequence and Phylogenetic Analysis of the TP53 Gene
Team
- Farah Mamdouh
- Nosaiba Elsayed
- Nada Magdi
- Sama Saleh
- Aya Abdullah
Group 5
BRCA1 protein
Comparative Sequence, Structural Architecture, and Phylogenetic Analysis of Breast Cancer Type 1 Susceptibility Protein (BRCA1) Across Vertebrate Species
Team
- Heba Rizk
- Nehal Ezzat
- Mark Magdy
- Samah Ibrahim
- Sama Said
Group 6
BRCA1 gene
Comparative Genomic and Phylogenetic Tree Analysis of BRCA1
Team
- Sarah Hakim
- Marwa Yousif
- Nada Baqi
- Rehab Abdalazime
- Hosam-Eldin Husien
Group 7
p53 protein
In Silico Comparative and Evolutionary Analysis of the p53 Protein Across Six Vertebrates and Its Mutation Hotspots
Team
- Sama Hamed
- Yasmeen Nabil
- Hiba Khair
- Aml Elsheikh
Group 8
EGFR protein
Comparative Bioinformatics Analysis of EGFR Protein Across Species
Team
- Esraa Yahia
- Bothaina Abdelaziz
- Nada Tarek
- Habiba Mohamed
- Fatma Radwan
Group 9
TP53 protein
Evolutionary Dynamics of TP53 Protein Structure and Domain Architecture Across Vertebrate Taxa
Team
- Sana Mostafa
- Esraa Shaheen
- Hager Abdelzain
- Haneen Walid
- Mazen Nabel
Group 10
TREM2 gene
TREM2 Comparative Analysis Across Species
Team
- Rahma Taher
- Amal Abdelmaged
- Amina Elmorsi
- Mehri Nouha
Group 11
TP53 gene
Is TP53 Conserved Across Species? A Comparative Analysis of TP53 mRNA
Team
- Nada Ali
- Shrouq Shawkat
- Marwa Ahmed
- Sohila Diaa
Summer 2026
Single Cell RNA-seq
Group 1
Lung Cancer Antigens
Single-Cell Characterization of Cancer–Testis Antigen Expression and Metastasis-Associated Malignant Cell States in Non-Small Cell Lung Cancer
Team
- Amina Kamal
- Munawar Hraib
- Nada Hossam
- Dilawer Charo
- Abdallah Hassan
Group 2
Macrophage Immunosuppression
Identification of a Stromal Immunosuppressive Barrier Orchestrated by SPP1+/C1QC+ Macrophages and CD8+ Exhausted T Cells Driving Gastric Cancer Immunotherapy Resistance
Team
- Neama Ali
- Hazem Abdelmoaty
- Retag Hafez
- Youssef Mohamed
- Iman El-Zehery
Group 3
Ovarian Cancer Niche
Single-Cell Transcriptomic Profiling of Epithelial–Niche Communication Across Non-Malignant Ovarian Tissues and Stage-Stratified High-Grade Serous Ovarian Cancer
Team
- Hiba Khair
- Taghreed Abdelghani
- Leqaa Mahdy
- Mariam Ahmed
- Nour Ibrahim
Group 4
Brain Metastases
Single-Cell Analysis Uncovers the Cellular Ecosystem of Human Brain Metastases
Team
- Abdelrahman Ibrahim
- Fayza Aziz
- Jasmine Hashem
- Rana Elromh
- Mostafa Hassanein
Group 5
Colorectal Cancer Immunology
Remodeling of the Immune and Stromal Cell Compartment by PD-1 Blockade in Mismatch Repair-Deficient Colorectal Cancer
Team
- Aya Abdullah
- Maroua MILIANI
- Sohyla Ismail
- Shahd Mostafa
- Mohamed Syed
Group 6
Neuroblastoma Microenvironment
Single-Cell Profiling of Microenvironmental Remodeling and T/NK Cell Dysfunction in Pre- and Post-Chemotherapy Neuroblastoma
Team
- Sana Hussein
- Nada Ali
- Alshymaa Hamza
- Shahd Elsaid
- Ahmed Mohamed
Group 7
Huntington's Disease Glia
Mapping the Glial Transcriptome in Huntington's Disease Using snRNAseq: Selective Disruption of Glial Signatures Across Brain Regions
Team
- Shayma Sweis
- Ali Nawar
- Menna Ali
- Menna Tawfik
- Eman Abadi
Group 8
Hepatocellular Carcinoma
Single-Cell Transcriptomic Analysis of Cellular Composition and Gene Expression in Primary and Metastatic Hepatocellular Carcinoma
Team
- Shahd Helmy
- Mariam Samir
- Ehap Awad
- Alzahraa Jad
- Raghad Aldeen
Group 9
Sepsis Immune Dysfunction
Deciphering Immune Dysregulation in Sepsis Through Single-Cell Transcriptomics Analysis
Team
- Mostafa Sameh
- Alaa Fathy
- Gannah Saleh
- Mohamed Hamed
- Almahdy Helal
Group 10
Alzheimer's Neurons
Why Do Some Hippocampal Neuronal Subtypes Undergo Extensive Transcriptional Remodeling in APP23 Mice Whereas Others Remain Relatively Preserved?
Team
- Mostafa Khaled
- Esraa Abdalla
- Aliaa Ali
- Menna-tullah Abdelkhalek
- Hala Mohamed
Group 11
Viral-Host Interaction
Deciphering the Viral-Host Interaction Using Single Cell RNA Sequencing
Team
- Hassan Ishag
- Asmaa Nasr
- Maii Saleh
- Amani El-Sayed
- Nader Nabil
Group 12
Glioblastoma Sensitivity
Drug and Single-Cell Gene Expression Integration Identifies Sensitive and Resistant Glioblastoma Cells
Team
- Mohammed Ali
- Hussein Seif
- Aya Hegab
- Menna Ahmed
- Basmala Sayed
Group 13
Colorectal Invasion
Stem-Like Malignant Cell States at the Invasive Border in Colorectal Cancer (scRNA-seq Re-analysis)
Team
- Nada Fawzy
- Marwan Waleed
- Fatma Ahmed
- Mohamed Jasim
- Mona Magdy
Fall 2026
Cancer Biology Seminar Series
Group 1
Review Article
Recent advances and discoveries in the mechanisms and functions of CAR T cells
Presenters
- Adel Adel
- Adham Hazem
- Rawan Al-Anwar
- Aya Habib
- Abdelrhman Mohamed
Group 2
Review Article
A guide to cancer immunotherapy: from T cell basic science to clinical practice
Presenters
- Marwan Ahmed
- Sara Saad
- Hager Haridy
- Mahmoud Elmamlok
- Haitham Ibrahim
Group 3
Review Article
Recent advances and discoveries in the mechanisms and functions of CAR T cells
Presenters
- Afaf Mohamed
- Ahmed Abdelhaly
- Assem Hebala
- Momen Ahmed
- Menna Ismail
Group 4
Review Article
Metastasis-Initiating Cells and Ecosystems
Presenters
- Esraa Shazly
- Andalus Mahmoud
- Safa Fadl
- Mariam Ebeed
- Sara Mohamed
Group 5
Review Article
Metastatic colonization by circulating tumour cells
Presenters
- Nada Elsayed
- Khalid Sameer
- Ramez Abdelrahman
- Shahd Abdelrahman
- Emy Ehab
Group 6
Review Article
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
Presenters
- Hana Refaat
- Marwa Yousif
- Samira Mohammed
- Hanan Attia
- Rahma Ismail
Group 7
Review Article
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
Presenters
- Yasmin Hussein
- Yomna Khaled
- Eslam Soliman
- Sohyla Ismail
- Mona El-Shami
Group 8
Review Article
Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets
Presenters
- Amira Lotfy
- Tasnim Qeshta
- Fatmaelzahra Badry
- Alzahraa Jad
- Rahma Mohamed
Group 9
Review Article
Why do patients with cancer die?
Presenters
- Mostafa Aly
- Refida Hasni
- Mohamed Tamer
- Mostafa Ibrahim
- Mira Seadky
Group 10
Review Article
TGFβ in Cancer
Presenters
- Fatma Othman
- Rahma Abdelshakour
- Sara Fouda
- Mariam Mostafa
