أبحــــاث ومقــــالات علميــــة
استكشــــف أبحــــاث منشــــورة فــــي مجــــلات علميــــة دوليــــة فــــي مجــــال البيولوجــــي والمعلوماتيــــة الحيويــــة
Master Thesis
During my master’s thesis, I investigated colorectal cancer heterogeneity using single-cell and spatial transcriptomics, uncovering cancer cell states like LGR5+ cancer stem cells, EMP1+ high-relapse cells, and proliferative states in distinct spatial niches. I also identified critical tumor-microenvironment interactions, including SPP1+ macrophages and FAP+ fibroblasts co-localizing near high-relapse cells, revealing a potential CCL15-CCR1 signaling circuit driving macrophage recruitment and tumor progression.
Harnessing STING signaling and natural killer cells overcomes PARP inhibitor resistance in homologous recombination deficient breast cancer
Pedretti, F., Abdalfttah, M., Pellegrino, B., Mateo-González, F., Martínez-Sanz, P., Herencia-Ropero, A., Òdena, A., Clavell-Revelles, P., Casali, G., Domenech, H., Monserrat, L., Papić, D., Mas Malavila, A., Pascual-Reguant, A., Eixarch, H., Guzmán, M., Rodríguez, O., Grueso, J., Simonetti, S., ...Serra, V. (2025)
STAMP: Single-cell transcriptomics analysis and multimodal profiling through imaging
Emanuele Pitino, Anna Pascual-Reguant, Felipe Segato-Dezem ..... Mohmed Abdalfttah, Adrienne E. Sullivan, Jasmine T. Plummer, Holger Heyn, Luciano G. Martelotto (2025)
Site-Specific Entry Factors Define Cellular Susceptibility to SARS-CoV-2 in Human Tissues
Mireia Vivas-Roca, Cristina Mancebo-Perez, Mohmed Abdalfttah, Ismael Balafkir, Aleix Benitez-Martinez, Victor Montal, Alba Gonzalez, Irene Mota-Gomez, Judith Grau-Exposito, View ORCID ProfileDaan KJ Pieren, Bibiana Planas, Joel Rosado, Maria Eugenia Semidey, Stefania Landolfi, Eloy Espin-Bassany, Enric Trilla, Vicenc Falco, Adria Curran, Joaquin Burgos, Maria J Buzon, Victor Guallar, Holger Heyn, Meritxell Genesca
In Silico Characterization of Toxin-Antitoxin Systems in Campylobacter Isolates Recovered from Food Sources and Sporadic Human Illness
Wadie, B., Abdalfttah, M, Yousef, A., Mouftah, S. F., Elhadidy, M., & Salem, T. Z Genes (2021)
Multigene panel sequencing reveals cancer-specific and common somatic mutations in colorectal cancer patients: an Egyptian experience
Youssef, A. S. E. D., Abdalfttah, M, Lotfy, M. M., Nassar, A., Abouelhoda, M., Touny, A. O., ... & Zekri, A. R. N. Current issues in molecular biology (2022)
Community assesses differential cell communication using large multi-sample case-control scRNAseq datasets
Solovey, M., Celik, M. A., Salcher, F. R., Abdalfttah, M., Ismail, M., Scialdone, A., ... & Colome-Tatche, M. Cell Reports, 2024
ابدأ رحلتــــك البحثيــــة الآن
متستناش أكتر — ابدأ تعلّــــم، طبّــــق، واطــــوّر نفســــك بخطــــوات حقيقيــــة توصّــــلك لمستــــوى أفضــــل
