DNA Structure
Welcome to DNA Structure Course!
This course is designed to provide a comprehensive understanding of DNA as the fundamental molecule of life. From its historical discovery to its intricate structure and chemical properties, participants will explore how DNA functions as the genetic blueprint of all living organisms. Throughout the course, we will examine the experimental evidence supporting DNA as the genetic material, delve into the molecular architecture of nucleic acids, and analyze the key differences between DNA and RNA. By the end, participants will have a solid grasp of DNA's role in genetics, inheritance, and molecular biology.
Why take this course?
- Gain a strong foundation in DNA structure and function, essential for understanding genetics and molecular biology.
- Explore the historical experiments that led to the discovery of DNA as genetic material.
- Understand the differences between DNA and RNA, and how they encode genetic information.
- Learn about nucleic acid chemistry, base pairing, and DNA stability with real scientific examples.
- Perfect for students, researchers, and professionals looking to strengthen their knowledge of molecular biology.
Course Content
Characteristics of Genetic Material
Replication, Storage, Expression, and Variation by Mutation
Early Theories: Protein vs. DNA as Genetic Material
Avery, MacLeod, and McCarty Experiment
Griffith’s Transformation Experiments
Hershey-Chase Experiment
Transformation Experiments
Transfection Studies
Indirect and Direct Evidence in Eukaryotes
Experimental Evidence of RNA in Viruses
Role of Retroviruses and Reverse Transcription
Structure of DNA and RNA
Nucleotides, Nucleosides, and Phosphates
Polynucleotides and DNA Stability
Chargaff’s Base Composition Studies
X-ray Diffraction and Rosalind Franklin’s Contribution
Watson and Crick Model of DNA Structure
Hydrogen Bonding in Base Pairs
Importance of Sugar-Phosphate Backbone
Alternative DNA Forms (A-DNA, B-DNA, Z-DNA)
Ribosomal RNA (rRNA)
Messenger RNA (mRNA)
Transfer RNA (tRNA)
Who Should Enroll?
- Undergraduate and graduate students in biology, biotechnology, genetics, and related fields.
- Researchers and professionals seeking a refresher on DNA structure and analysis.
- Science enthusiasts curious about how genetic information is stored and transmitted.
- Aspiring geneticists and bioinformaticians who want a strong molecular foundation.

Mohmed Abdalfttah
InstructorPhD Candidate
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